Vitamin D is not technically a vitamin or essential dietary factor. Vitamin D is actually a pro-hormone produced phytochemically in the skin. And unlike traditional vitamins, Vitamin D has its own hormone receptor (VDR). VDRs are found in at least 36 different organs in the body. To further establish this fact and to see if Vitamin D3 may actually have an anabolic effect, researchers carried out an in-vitro study using muscle cells, insulin, leucine, and Vitamin D. The focus of this study was on the mTOR anabolic signaling pathway in muscle cells. It is well known that insulin facilitates the activation of the mTOR pathway, particularly high insulin levels. Leucine is a direct activator of the mTOR pathway and in this way can “switch on” protein synthesis in muscle cells. These researchers took muscle cells and exposed them to leucine and insulin, or leucine, insulin, and Vitamin D. Results demonstrated that the addition of Vitamin D to insulin and leucine significantly enhanced the activity of the mTOR pathway and protein synthesis. The authors conclude that Vitamin D has the potential to directly alter protein synthesis in muscle cells . Additionally, several studies have found that low vitamin D is associated with low testosterone levels. One study found out that men with sufficient vitamin D levels had significantly higher testosterone levels and lower SHBG count, than men who had insufficient amounts of the vitamin (or hormone) in their blood serum. Another study found out that when healthy male participants take 3332 IU’s of vitamin D daily for a year, they end up having 25,2% more testosterone on average when compared to placebo. Getting out in the sun maybe be more than just relaxing, it may be anabolic for bodybuilders!
Allergies occur when an exaggerated immune response occurs in reaction to a pathogen. Steroids treat the allergies by suppressing the immune system – or more precisely, inhibit T cell activity. This is where conventional vets and holistic vets will part ways. Using steroids to control allergies is merely suppressing symptoms – and causing dangerous side effects including a suppressed immune system, softening of the bones, muscle weakness, diabetes and liver disease. Holistic vets are much more interested in restoring balance to the immune system – and avoiding the dangerous side effects of drugs.