Although evidence for the use of topical antibiotics in an uncomplicated corneal abrasion is lacking, they are usually prescribed with the rationale of preventing superinfection. 4 , 16 , 17 Topical antibiotics are indicated for corneal abrasions caused by contact lens use, foreign bodies, or a history of trauma with infectious or vegetative matter, because there is a higher risk of secondary bacterial keratitis in these cases. 18 For uncomplicated abrasions, options include erythromycin % ophthalmic ointment, polymyxin B/trimethoprim (Polytrim) ophthalmic solution, and sulfacetamide 10% ophthalmic ointment or solution ( Table 2 ) . Topical antibiotics are generally dosed four times a day and continued until the patient is asymptomatic for 24 hours. Ointments are thought to provide better lubrication than solutions, resulting in increased comfort and healing. Preparations containing neomycin should be avoided because of the frequency of contact hypersensitivity. Combination preparations with a topical steroid are contraindicated because topical steroids increase susceptibility to infection and may delay healing. 19
Other causes of iritis include idiopathic (of unknown origin) iritis, infectious (herpes zoster, toxoplasmosis, tuberculosis, histoplasmosis, syphilis) iritis, genetic (HLA-B27, ankylosing spondylitis, Reiter’s syndrome, psoriatic arthritis), medications (antibiotics, antivirals), associated with systemic diseases (juvenile rheumatoid arthritis, inflammatory bowel disease, down’s syndrome, Behcet’s syndrome), nongranulomatous anterior uveitis, extension of posterior uveitis, hyphema, corneal abrasion, or retinal detachment. 
Keratoconus, which occurs in 1 out of every 2,000 persons, is an irregular bulging of the central area of the cornea. The condition is due to weakening and thinning of the central portion of the cornea causing a change in shape of the central portion of the cornea. The cornea becomes more conical and distorted causing significant changes in vision which may begin in the late teen years and may not stop until age 40. In some patients keratoconus appears to be an inherited bilateral (two eye) condition, while in other patients there is no evidence of a inherited disorder.