As previously mentioned, Major League Baseball did not have anabolic steroid testing procedures or even any bans until long after many other major sports leagues and organizations implemented them. It was not until the late 1990s and early 2000s that anabolic steroids became an issue brought to the forefront in the MLB and in the media. During the early 2000s, a reporter had supposedly spotted a bottle of Androstenedione in Mark McGwire’s locker, which was a legal nutritional supplement at the time. Androstenedione is a prohormone, which is a precursor hormone to anabolic steroids. On their own, prohormones possess little to zero hormonal activity. It is not until prohormones are consumed by the human body, where the liver undergoes conversion of the prohormone through various biochemical reactions and processes to form the end result, which is an active anabolic steroid hormone. The development of prohormones and the bioactive mechanism through which they work effectively avoided the laws surrounding anabolic steroids. The result was the free sale and purchase of prohormone supplements on the shelves of any supplement store.
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